张玥

发布者:花文婷发布时间:2022-09-27浏览次数:11

 

职称:副教授    E-mail:zhangyue035@njucm.edu.cn      主要研究方向:核酸探针的开发设计及其在中药快速鉴定中的应用

 

个人简介

       2020年博士毕业于南京大学,2021年入选江苏省双创博士人才计划,在J. Am. Chem. Soc.Angew. Chem.等国际一流期刊发表文章10余篇。主持国家自然科学基金项目1项,江苏省自然科学基金项目1项,国家重点实验室开放基金1项。

 

承担的主要科研项目

国家自然科学基金青年项目(22104063,通用型DNA纳米卫星平台的构建及其在疾病诊疗的应用,2022/01-2024/12,主持30,在研

江苏省自然科学基金青年项目(SBK2021042488DNA纳米线团的设计及其在肿瘤成像和治疗中的应用,2021/07-2024/06,主持20,在研

南京大学生命分析化学国家重点实验室开放课题(SKLACLS2109,金-DNA纳米复合体应用于中药活性分子的负载与释放监控,2021/04-2022/12,主持5,在研

 

 代表性论文

[1] Yue Zhang#, Weiwei Chen#, Yanyun Fang, Xiaobo Zhang, Ying Liu*, Huangxian Ju*. Activating a DNA Nanomachine via Computation across Cancer Cell Membranes for Precise Therapy of Solid Tumors. Journal of the American Chemical Society 143 (2021) 15233-15242. (IF: 14.6950).

[2] Yue Zhang, Xiaobo Zhang, Yuling He, Ying Liu*, Huangxian Ju*. Self-assembled micelle responsive to quick NIR light irradiation for fast drug release and highly efficient cancer therapy. Journal of Controlled Release 336 (2021) 469-479. (IF: 7.901).

[3] Yue Zhang#, Weiwei Chen#, Yue Zhang, Xiaobo Zhang, Ying Liu*, Huangxian Ju*. A near-infrared photo-switched microRNA amplifier for precise photodynamic therapy of early-stage cancers. Angewandte Chemie-International Edition 59 (2020) 21454-21459. (IF: 12.257). 

[4] Yue Zhang, Yue Zhang, Guobin Song, Yuling He, Xiaobo Zhang, Ying Liu*, Huangxian Ju*. A DNA-azobenzene nanopump fueled by upconversion luminescence for controllable intracellular drug release. Angewandte Chemie-International Edition 58 (2019) 18207-18211. (IF: 12.257). 

[5] Yue Zhang, Kewei Ren, Xiaobo Zhang, Zhicong Chao, Yuqin Yang, Deju Ye, Zhihui Dai, Ying Liu*, Huangxian Ju*. Photo-tearable tape close-wrapped upconversion nanocapsules for near-infrared modulated efficient siRNA delivery and therapy. Biomaterials 163 (2018) 55-66. (IF: 10.273).

[6] Kewei Ren#, Yue Zhang#, Xiaobo Zhang, Ying Liu*, Huangxian Ju*. In situ siRNA assembly in living cells for gene therapy with microRNA triggered cascade reactions templated by nucleic acids. ACS Nano 12 (2018), 10797-10806. (IF: 13.903).(共同第一作者

 

获得奖项与荣誉

2021年江苏省双创博士人才计划

 


 




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